The production of hexamethylenediamine (HMDA) involves a series of chemical reactions that convert raw materials into this valuable compound. The most common industrial method begins with the hydrocyanation of butadiene to produce adiponitrile. This reaction is facilitated by the presence of hydrogen cyanide and a suitable catalyst.

Following the formation of adiponitrile, the compound undergoes hydrogenation in the presence of a catalyst, typically cobalt or iron-based, to yield HMDA. An alternative method employs Raney nickel as a catalyst, using HMDA itself as a solvent, which operates under milder conditions.

The purity of the final HMDA product is crucial for its intended applications. Therefore, the production process includes purification steps to remove any residual impurities and by-products, ensuring the quality and consistency of the compound.

Advancements in production technologies continue to improve the efficiency and sustainability of HMDA manufacturing, aiming to meet the growing demand across various industries.